imageCannabis, and the cannabinoid compounds found within it, has been shown through a large  amount of scientific, peer-reviewed research to be effective at treating a wide variety of cancers, ranging from brain cancer to colon cancer. Below is a list of over 60 studies that demonstrate the vast anti-cancer properties of cannabis.

  • Cannabidiol (CBD) inhibits the proliferation and invasion in U87-MG and T98G glioma cells. Study published in the Public Library of Science[1] journal in October 2013.
  • Tetrahydrocannabinol (THC) can kill cancer cells by causing them to self-digest. Study published in the Journal of Clinical Investigation[2] in September 2013.
  • CBD is a novel therapeutic target against glioblastoma. Study published in Cancer Research[3] in March 2013.
  • Local delivery of cannabinoid-filled microparticles inhibits tumor growth in a model of glioblastoma multiforme. Study published in Public Library of Science[4] in January 2013.
  • Cannabinoid action inhibits the growth of malignant human glioma U87MG cells. Study published in Oncology Reports[5] in July 2012.
  • Cannabidiol enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival. Study published in the Molecular Cancer Therapeutics[6] journal in January 2010.
  • Cannabinoid action induces autophagy-mediated cell death in human glioma cells. Study published in The Journal of Clinical Investigation[7] in May 2009.
  • Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Study published in Cancer Research[8] in March 2008.
  • Cannabinoids and gliomas. Study published in Molecular Neurobiology[9] in June 2007.
  • Cannabinoids inhibit gliomagenesis. Study published in the Journal of Biological Chemistry[10] in March 2007.
  • A pilot clinical study of THC in patients with recurrent glioblastoma multiforme. The results were published in the British Journal of Cancer[11] in June 2006.
  • Cannabidiol inhibits human glioma cell migration through an independent cannabinoid receptor mechanism. Study published in the British Journal of Pharmacology[12] in April 2005.
  • Cannabinoids inhibit the vascular endothelial growth factor pathway (VEGF) in gliomas. Study published in the Journal of Cancer Research[13] in August 2004.
  • Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. Study published in the Journal of Pharmacology[14] in November 2003.
  • Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Study published in the Journal of Cancer Research [15]in August 2001.
  • Cannabigerol (CBG) can inhibit colon cancer cells. Study published in the Oxford journal Carcinogenesis[16] in October 2014.
  • Inhibition of colon carcinogenesis by a standardised Cannabis Sativa extract with high content of CBD. Study published in Phytomedecine[17] in December 2013.
  • Chemopreventive effect of the non-psychotropic phytocannabinoid CBD on colon cancer. Study published in the Journal of Molecular Medecine[18] in August 2012.
  • Cannabinoids against intestinal inflammation and cancer. Study published in Pharmacology Research[19] in August 2009.
  • Action of cannabinoid receptors on colorectal tumor growth. Study published by the Cancer Center of the University of Texas[20] in July 2008.
  • Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of Icam-1. Study published in Biochemical Pharmacology[28] in July 2014.
  • Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Study published in Biochemical Pharmacology[29] in June 2014.
  • COX-2 and PPAR-γ confer CBD-induced apoptosis of human lung cancer cells. Study published in Molecular Cancer Therapeutics[30] in January 2013.
  • CBD inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. Study published in the Journal of the Federation of American Societies for Experimental Biology[31] in April 2012.
  • Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non–small cell lung cancer growth and metastasis. Study published in Cancer Prevention Research[32] in January 2011.
  • THC inhibits epithelial growth factor-induced (EGF) lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Study published in the journal Oncogene[33] in July 2007.
  • Cannabinoid receptor agonist as an alternative drug in 5-Fluorouracil-resistant gastric cancer cells. Study published in Anticancer Research[34] in June 2013.
  • Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. Study published in the Journal of Cellular Biochemistry[35] in March 2011.
  • Cannabinoids may provide a treatment option for prostate cancer that has become nonresponsive to common therapy, according to a study[36] published in the February issue of the journal Oncology Reports, and published online by the National Institute of Health.
  • Cannabinoids can treat prostate cancer. Study published by the National Institute of Health[37] in October 2013.
  • Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms. Study published in the British Journal of Pharmacology[38] in December 2012.
  • The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications. Study published in the Indian Journal of Urology[39] in January 2012.
  • Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. Study published in Anticancer Research[40] in November 2011.
  • Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (CHC). Study published in Cell Death and Disease[41] in May 2013.
  • Evaluation of anti-invasion effect of cannabinoids on human hepatocarcinoma cells. Study published on the site Informa Healthcare[42] in February 2013.
  • Antitumoral action of cannabinoids on hepatocellular carcinoma. Study published in Cell Death and Differentiation[43] in April 2011.
  • Cannabinoids inhibit energetic metabolism and induce autophagy in pancreatic cancer cells. Study published in Cell Death and Disease[44] in June 2013.
  • Cannabinoids Induce apoptosis of pancreatic tumor cells. Study published in Cancer Research[45] in July 2006.
  • A study[46] published in the February, 2015 edition of the journal Molecular Oncology, and published online by the National Institute of Health, found that the cannabis compound cannabidiol inhibits the growth and metastasis of highly aggressive breast cancer.
  • Cannabis use is associated with reduced incidences of bladder cancer, according to a study[47] published in the February, 2015 issue of the journal Urology.
  • Bladder: Marijuana reduces the risk of bladder cancer. Study published in the Medscape[48] site in May 2013.
  • Kaposi sarcoma: Cannabidiol inhibits growth and induces programmed cell death in Kaposi sarcoma–associated herpesvirus-infected endothelium. Study published in the journal Genes & Cancer[49] in July 2012.
  • Nose, mouth, throat, ear: Cannabinoids like THC inhibit cellular respiration of human oral cancer cells. Study by the Department of Pediatrics at the State University of New York[50], published in June 2010.
  • Bile duct: The dual effects of THC on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration. Study published in Cancer Investigation [51]in May 2010.
  • Ovaries: Cannabinoid receptors as a target for therapy of ovarian cancer. Study published on the American Association for Cancer Research[52] website in 2006.

[Editor’s Note: This article was originally published on October 7th, 2014, but was updated on August 16th, 2015.]

TheJointBlog

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